{
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  "Package": "BuyseTest",
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  "Title": "Generalized Pairwise Comparisons",
  "Version": "3.4.0",
  "Date": "2026-09-25",
  "Authors@R": "c(\nperson(\"Brice\", \"Ozenne\", role = c(\"aut\", \"cre\"), email = \"brice.mh.ozenne@gmail.com\", comment = c(ORCID = \"0000-0001-9694-2956\")),\nperson(\"Eva\", \"Cantagallo\", role = \"aut\"),\nperson(\"William\", \"Anderson\", role = \"aut\"),\nperson(\"Julien\", \"Peron\", role = \"ctb\"),\nperson(\"Johan\", \"Verbeeck\", role = \"ctb\")\n)",
  "Description": "Implementation of the Generalized Pairwise Comparisons\n(GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for\ncomplete observations, and extended in Peron (2018)\n<doi:10.1177/0962280216658320> to deal with right-censoring.\nGPC compare two groups of observations (intervention vs.\ncontrol group) regarding several prioritized endpoints to\nestimate the probability that a random observation drawn from\none group performs better/worse/equivalently than a random\nobservation drawn from the other group. Summary statistics such\nas the net treatment benefit, win ratio, or win odds are then\ndeduced from these probabilities. Confidence intervals and\np-values are obtained based on asymptotic results (Ozenne 2021\n<doi:10.1177/09622802211037067>), non-parametric bootstrap, or\npermutations. The software enables the use of thresholds of\nminimal importance difference, stratification, non-prioritized\nendpoints (O Brien test), and can handle right-censoring and\ncompeting-risks.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "URL": "https://github.com/bozenne/BuyseTest",
  "BugReports": "https://github.com/bozenne/BuyseTest/issues",
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  "Repository": "https://bozenne.r-universe.dev",
  "Date/Publication": "2026-09-25 09:54:34 UTC",
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  "Author": "Brice Ozenne [aut, cre] (ORCID:\n<https://orcid.org/0000-0001-9694-2956>),\nEva Cantagallo [aut],\nWilliam Anderson [aut],\nJulien Peron [ctb],\nJohan Verbeeck [ctb]",
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  "_created": "2026-10-25T11:58:26.000Z",
  "_published": "2026-10-25T12:16:30.348Z",
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    {
      "page": "BuyseTest-package",
      "title": "BuyseTest package: Generalized Pairwise Comparisons",
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        "BuyseTest-package"
      ]
    },
    {
      "page": "dot-colCenter_cpp",
      "title": "Substract a vector of values in each column",
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      ]
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    {
      "page": "dot-colCumSum_cpp",
      "title": "Column-wise cumulative sum",
      "topics": [
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    {
      "page": "dot-colMultiply_cpp",
      "title": "Multiply by a vector of values in each column",
      "topics": [
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      ]
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      "page": "dot-colScale_cpp",
      "title": "Divide by a vector of values in each column",
      "topics": [
        ".colScale_cpp"
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    {
      "page": "dot-rowCenter_cpp",
      "title": "Substract a vector of values in each row",
      "topics": [
        ".rowCenter_cpp"
      ]
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    {
      "page": "dot-rowCumProd_cpp",
      "title": "Apply cumprod in each row",
      "topics": [
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      "title": "Row-wise cumulative sum",
      "topics": [
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    {
      "page": "dot-rowMultiply_cpp",
      "title": "Multiply by a vector of values in each row",
      "topics": [
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      "title": "Dividy by a vector of values in each row",
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      "title": "Convert Performance Objet to data.table",
      "topics": [
        "as.data.table.performance"
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      "title": "Estimation of the Area Under the ROC Curve (EXPERIMENTAL)",
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        "auc"
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      "title": "Graphical Display for GPC",
      "topics": [
        "autoplot.S4BuyseTest"
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      "title": "Estimation of the Brier Score (EXPERIMENTAL)",
      "topics": [
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      "title": "Adjustment for Multiple Comparisons",
      "topics": [
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    {
      "page": "BuyseTest",
      "title": "Two-group GPC",
      "topics": [
        "BuyseTest"
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      "title": "Global options for BuyseTest package",
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      "title": "Methods for the class \"BuyseTest.options\"",
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        "BuyseTest.options-methods",
        "select,BuyseTest.options-method"
      ]
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        "BuyseTTEM",
        "BuyseTTEM.BuyseTTEM",
        "BuyseTTEM.formula",
        "BuyseTTEM.prodlim",
        "BuyseTTEM.survreg"
      ]
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        "CasinoTest"
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      "topics": [
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      "topics": [
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      "title": "Extract the Brier Score",
      "topics": [
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      "title": "Extract the AUC value with its Confidence Interval",
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        "confint.BuyseTestAuc"
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      "page": "confint.BuyseTestBrier",
      "title": "Extract the Brier Score with its Confidence Interval",
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      "title": "Constrained Kaplan-Meier Estimator",
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      "page": "getCount",
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      "page": "data-prodige",
      "title": "RCT In Metastatic Pancreatic Cancer Comparing Two Chemoterapy.",
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